protein

DSC2/Desmocollin-2 Protein, Human (HEK293, His)

HY-P76301

5 μg;10 μg;50 μg;100 μg

40;68;190;290 USD

DSC2/Desmocollin-2 Protein, Human (HEK293, His)

proteins

HEK293

5 μg;10 μg;50 μg;100 μg

40;68;190;290 USD

DSC2/Desmocollin-2 protein is vital for intercellular desmosome junctions, mediating adhesion by interacting with plaque proteins and intermediate filaments. It also regulates cell positioning and interacts with DSP, PKP2, and JUP, strengthening junction stability. Overall, DSC2/Desmocollin-2 protein maintains tissue organization and functionality. DSC2/Desmocollin-2 Protein, Human (HEK293, His) is the recombinant human-derived DSC2/Desmocollin-2 protein, expressed by HEK293 , with C-His labeled tag. The total length of DSC2/Desmocollin-2 Protein, Human (HEK293, His) is 657 a.a., with molecular weight of ~85 & 100 KDa, respectively.

Human

DSC2/Desmocollin-2 protein is a critical component of intercellular desmosome junctions, playing a crucial role in facilitating cell-cell adhesion by mediating the interaction between plaque proteins and intermediate filaments. In addition to its adhesive function, DSC2 may also contribute to epidermal cell positioning by regulating the adhesiveness between cells expressing different isoforms. This protein interacts with DSP, PKP2, and JUP, further reinforcing the stability and integrity of these junctions. By participating in these molecular interactions, DSC2/Desmocollin-2 protein ensures the proper organization and functionality of tissues.

Cadherin family member 2; CDHF2; DSC3; Desmosomal glycoprotein II

Greater than 90% as determined by reducing SDS-PAGE.

Supplied as a 0.2 μm filtered solution of PBS, pH 7.4.

Shipping with dry ice