protein

CD1B-B2M Heterodimer Protein, Rhesus Macaque (HEK293, His)

HY-P76209

5 μg;10 μg;50 μg

60;95;250 USD

CD1B-B2M Heterodimer Protein, Rhesus Macaque (HEK293, His)

proteins

HEK293

5 μg;10 μg;50 μg

60;95;250 USD

CD1B belongs to family 1 of the transmembrane glycoprotein CD1 family and plays a critical role in immune surveillance and response. As a key antigen-presenting molecule, CD1B protein has shown the ability to bind both self and non-self-lipid and glycolipid antigens. CD1B is a potential prognostic biomarker associated with tumor mutation burden and promotes antitumor immunity in lung adenocarcinoma. CD1B-B2M Heterodimer Protein, Rhesus Macaque (HEK293, His) is a recombinant protein dimer complex containing Rhesus Macaque-derived CD1B-B2M Heterodimer protein, expressed by HEK293 , with C-His labeled tag. CD1B-B2M Heterodimer Protein, Rhesus Macaque (HEK293, His), has molecular weight of ~38-45 & 12 KDa.

Rhesus Macaque

CD1B belongs to Group 1 of the transmembrane glycoprotein CD1 family. The CD1 molecule is expressed on the surface of many different human antigen-presenting cells (DC, monocytes, and some thymus cells). The CD1B protein, as a key antigen-presenting molecule, has shown the ability to bind both self and non-self lipid and glycolipid antigens, thereby facilitating their presentation to T cell receptors on natural killer T cells. This protein forms a heterodimer complex with B2M (beta-2 microglobulin), which plays a crucial role in immune surveillance and response. Its interaction with saponin C further enhances its functional library, helping T cells to recognize and activate the complex process of various antigens. CD1B is a potential prognostic biomarker associated with tumor mutation burden and promotes antitumor immunity in lung adenocarcinoma [1] [2] [3] .

T-cell surface glycoprotein CD1b; CD1B; Beta-2-microglobulin; B2M

Greater than 95% as determined by reducing SDS-PAGE

Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.

Room temperature in continental US; may vary elsewhere.