protein

VHL Protein, Human (His)

HY-P76124

5 μg;10 μg;20 μg;50 μg;100 μg

155;265;450;810;1260 USD

VHL Protein, Human (His)

Protein

E. coli

5 μg;10 μg;20 μg;50 μg;100 μg

155;265;450;810;1260 USD

VHL protein is an important component of the von Hippel-Lindau ubiquitination complex and plays a key role in ubiquitination and proteasomal degradation. As a target recruitment subunit in the E3 ubiquitin ligase complex, VHL specifically recruits hydroxylated hypoxia-inducible factor (HIF) under normoxic conditions and regulates cellular responses to oxygen levels. VHL Protein, Human (His) is the recombinant human-derived VHL protein, expressed by E. coli , with N-6*His labeled tag.