protein

SMYD3 Protein, Human (sf9, GST)

HY-P76080

20 μg;50 μg

250;550 USD

SMYD3 Protein, Human (sf9, GST)

proteins

Sf9 insect cells

20 μg;50 μg

250;550 USD

SMYD3 Protein, a histone methyltransferase, specifically induces di- and tri-methylation of H3K4, avoiding monomethylation, and methylates H4K5. Crucial in transcriptional activation within an RNA polymerase complex, SMYD3 also exhibits DNA-binding affinity for sequences containing 5'-CCCTCC-3' or 5'-GAGGGG-3'. SMYD3 Protein, Human (sf9, GST) is the recombinant human-derived SMYD3 protein, expressed by Sf9 insect cells , with N-GST labeled tag. The total length of SMYD3 Protein, Human (sf9, GST) is 335 a.a., with molecular weight of ~58 kDa.

Human

SMYD3 Protein, a histone methyltransferase, exhibits specificity in methylating 'Lys-4' of histone H3, inducing both di- and tri-methylation but not monomethylation. Additionally, it methylates 'Lys-5' of histone H4. Within an RNA polymerase complex, SMYD3 plays a crucial role in transcriptional activation. The protein is noted for its ability to bind DNA sequences containing 5'-CCCTCC-3' or 5'-GAGGGG-3'.

Histone-lysine N-methyltransferase SMYD3; ZMYND1; ZNFN3A1

Greater than 88% as determined by reducing SDS-PAGE

Lyophilized from a 0.2 μm filtered solution of 20 mM Tris, 150 mM NaCl, 0.5 mM DTT, 0.5 mM GSH, pH 8.0. Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween 80 are added as protectants before lyophilization.

Room temperature in continental US; may vary elsewhere.