ARMET/MANF Protein, Human (HEK293, His) | MedChem Express LLC HY-P7605 product information

product summary

company name :

MedChem Express LLC

product type :

protein

product name :

ARMET/MANF Protein, Human (HEK293, His)

catalog :

HY-P7605

quantity :

10 μg;50 μg

price :

105;314 USD

more info or order :

MedChem Express LLC product webpage

product information

Catalog Number :

HY-P7605

Product Name :

ARMET/MANF Protein, Human (HEK293, His)

Product Type :

proteins

Host Species :

HEK293

Size :

10 μg;50 μg

List Price :

105;314 USD

Product Description :

ARMET/MANF Protein, Human (HEK293, His) expresses in HEK293 cells with a His tag. Armet/MANF, localized in the ER and Golgi, is a secreted protein and acts as a gene up-regulated by various forms of ER stress [1] .

SpeciesSummary :

Human

Background :

Armet (also known as MANF) acts as a gene up-regulated by various forms of ER stress in different cell lines and by cerebral ischaemia in rat. Armet interacts with mutant matrilin-3. Armet is a genotype-specific ER stress response protein with substrate specificities, and that aggregation of mutant matrilin-3 is a key disease trigger in multiple epiphyseal dysplasia (MED) that could be exploited as a potential therapeutic target [1] .

ALTnames :

rHuARMET/MANF, His; Mesencephalic astrocyte-derived neurotrophic factor; ARMET

Purity :

Greater than 95% as determined by reducing SDS-PAGE.

Buffer :

Lyophilized after extensive dialysis against 20 mM PB,150 mM NaCl, pH7.4.

Storage :

Room temperature in continental US; may vary elsewhere.

more info or order :

MedChem Express LLC product webpage