AKR1C3 Protein, Human (HEK293, His) | MedChem Express LLC HY-P7604 product information

product summary

company name :

MedChem Express LLC

product type :

protein

product name :

AKR1C3 Protein, Human (HEK293, His)

catalog :

HY-P7604

quantity :

10 μg;50 μg

price :

150;400 USD

more info or order :

MedChem Express LLC product webpage

product information

Catalog Number :

HY-P7604

Product Name :

AKR1C3 Protein, Human (HEK293, His)

Product Type :

proteins

Host Species :

HEK293

Size :

10 μg;50 μg

List Price :

150;400 USD

Product Description :

AKR1C3 Protein, Human (HEK293, His) expresses in HEK293 cells with a His tag. Aldo-keto reductase family 1 member C3 (AKR1C3) is a steroidogenic enzyme that plays a crucial role in the conversion of adrenal androgen dehydroepiandrosterone (DHEA) into high-affinity ligands for the androgen receptor (testosterone [T] and dihydrotestosterone [DHT]) [1] .

SpeciesSummary :

Human

Background :

AKR1C3, an enzyme involved in the conversion of adrenal androgens into testosterone, is often upregulated in castration-resistant prostate cancer (CRPC). AKR1C3 could be a marker for intratumoral steroidogenesis and subsequently could become a target for secondary hormonal treatment of CRPC [1] .

ALTnames :

rHuAKR1C3, His; AKR1C3; HA1753; Dihydrodiol Dehydrogenase Type I; Indanol Dehydrogenase; Prostaglandin F Synthase

Purity :

Greater than 95% as determined by reducing SDS-PAGE.

Buffer :

Lyophilized from a 0.2 μm filtered solution of 20 mM PB, 6% Sucrose, 2% Glycine, 100 mM NaCl, 0.05% Tween 80, pH 6.0.

Storage :

Room temperature in continental US; may vary elsewhere.

more info or order :

MedChem Express LLC product webpage