protein

RAB1B Protein, Human (HEK293, Fc)

HY-P75993

5 μg;10 μg;50 μg;100 μg

40;70;200;340 USD

RAB1B Protein, Human (HEK293, Fc)

proteins

HEK293

5 μg;10 μg;50 μg;100 μg

40;70;200;340 USD

The RAB1B protein is an important small GTPase that regulates intracellular membrane trafficking by coordinating vesicular processes through cycling between GDP and GTP forms. It recruits downstream effectors to achieve vesicle functions, including formation, movement, and fusion. RAB1B Protein, Human (HEK293, Fc) is the recombinant human-derived RAB1B protein, expressed by HEK293 , with N-hFc labeled tag. The total length of RAB1B Protein, Human (HEK293, Fc) is 199 a.a., with molecular weight of ~58 kDa.

Human

The small GTPase Rab1B is a crucial regulator of intracellular membrane trafficking, orchestrating various stages from the formation of transport vesicles to their fusion with membranes. Operating through a cycle between an inactive GDP-bound form and an active GTP-bound form, Rab1B plays a pivotal role in recruiting downstream effectors responsible for vesicle processes, including formation, movement, tethering, and fusion. Notably, Rab1B contributes to the early stages of autophagic vacuole development, particularly at specialized regions of the endoplasmic reticulum. Additionally, it is involved in regulating vesicular transport between the endoplasmic reticulum and successive Golgi compartments, influencing the compacted morphology of the Golgi and facilitating the recruitment of lipid phosphatase MTMR6 to the endoplasmic reticulum-Golgi intermediate compartment.

Ras-related protein Rab-1B; RAB1B

Greater than 90% as determined by reducing SDS-PAGE.

Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.

Room temperature in continental US; may vary elsewhere.