protein

PSME2 Protein, Human (His)

HY-P75991

5 μg;10 μg;50 μg

40;70;200 USD

PSME2 Protein, Human (His)

proteins

E. coli

5 μg;10 μg;50 μg

40;70;200 USD

PSME2 Protein, vital for immunoproteasome assembly, is crucial for efficient antigen processing. In collaboration with PSME1, the PA28 activator complex modifies the proteasome's cleavage pattern, actively contributing to class I binding peptide generation. The hexameric ring structure of this heterodimeric complex underscores its significance in orchestrating processes essential for immune responses and antigen presentation. PSME2 Protein, Human (His) is the recombinant human-derived PSME2 protein, expressed by E. coli , with N-His labeled tag. The total length of PSME2 Protein, Human (His) is 239 a.a., with molecular weight of ~29 kDa.

Human

PSME2 Protein plays a crucial role in immunoproteasome assembly and is essential for efficient antigen processing. The PA28 activator complex, composed of PSME1 and PSME2 heterodimer, actively contributes to the generation of class I binding peptides by modifying the cleavage pattern of the proteasome. This heterodimeric complex forms a hexameric ring structure, highlighting its significance in orchestrating processes vital for immune responses and antigen presentation.

Proteasome activator complex subunit 2; REG-beta; PA28beta; PA28b; PSME2

Greater than 90% as determined by reducing SDS-PAGE

Lyophilized from a 0.2 μm filtered solution of 50 mM Tris-HCL, 300 mM NaCl, pH 8.0, 10% Glycerol.

Room temperature in continental US; may vary elsewhere.