protein

PSME1 Protein, Human (His)

HY-P75990

5 μg;10 μg;50 μg;100 μg;500 μg;1 mg

45;70;200;340;950;1500 USD

PSME1 Protein, Human (His)

proteins

E. coli

5 μg;10 μg;50 μg;100 μg;500 μg;1 mg

45;70;200;340;950;1500 USD

The PSME1 protein is critical for immunoproteasome assembly and is essential for efficient antigen processing. As part of the PA28 activator complex, PSME1, together with PSME2, actively enhances the production of class I binding peptides by altering the cleavage pattern of the proteasome. PSME1 Protein, Human (His) is the recombinant human-derived PSME1 protein, expressed by E. coli , with N-6*His labeled tag. The total length of PSME1 Protein, Human (His) is 248 a.a., with molecular weight of ~29 kDa.

Human

PSME1 Protein plays a pivotal role in immunoproteasome assembly and is crucial for efficient antigen processing. As a component of the PA28 activator complex, PSME1, along with PSME2, actively enhances the production of class I binding peptides by modulating the cleavage pattern of the proteasome. Together, the PSME1 and PSME2 heterodimer forms a hexameric ring structure integral to these immunoproteasome functions. Additionally, PSME1 has the capacity to form homoheptamers, further emphasizing its role in orchestrating immune responses and antigen presentation.

Proteasome activator complex subunit 1; REG-alpha; IGUP I-5111; PA28a; IFI5111

Greater than 90% as determined by reducing SDS-PAGE

Lyophilized from a 0.2 μm filtered solution of sterile 50 mM Tris, 300 mM NaCl, 5% trehalose, 5% mannitol and 0.01% Tween 80, pH 7.4.

Room temperature in continental US; may vary elsewhere.