protein

PRELP Protein, Human (HEK293)

HY-P75980

5 μg;10 μg;50 μg;100 μg

50;80;200;300 USD

PRELP Protein, Human (HEK293)

proteins

HEK293

5 μg;10 μg;50 μg;100 μg

50;80;200;300 USD

The PRELP protein may be an anchoring factor that plays a crucial role in connecting the basement membrane and connective tissue, contributing to structural integrity. Its interaction with the heparan sulfate proteoglycan perlecan and type I and type II collagen emphasizes its versatile binding ability. PRELP Protein, Human (HEK293) is the recombinant human-derived PRELP protein, expressed by HEK293 , with tag free. The total length of PRELP Protein, Human (HEK293) is 362 a.a., with molecular weight of ~54 kDa.

Human

PRELP Protein emerges as a potential anchoring factor linking basement membranes to the underlying connective tissue, suggesting a crucial role in structural integrity. This function implies its involvement in maintaining the stability and organization of extracellular matrices. PRELP specifically interacts with the basement membrane heparan sulfate proteoglycan perlecan and triple helical collagens type I and type II, underscoring its versatile binding capabilities and its significance in mediating molecular connections within the extracellular environment. The protein's dual ability to anchor to perlecan and collagens hints at its role in orchestrating the intricate composition of basement membranes, reflecting its potential contributions to tissue architecture and homeostasis. Further exploration of PRELP's interactions and functions may unveil its specific mechanisms in basement membrane anchoring and provide insights into its broader implications in connective tissue biology.

Prolargin; Proline-arginine-rich end leucine-rich repeat protein; PRELP; SLRR2A

Greater than 95% as determined by reducing SDS-PAGE

Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4, 8% trehalose.

Room temperature in continental US; may vary elsewhere.