protein

PFKP Protein, Human (sf9, His-GST)

HY-P75971

50 μg

720 USD

PFKP Protein, Human (sf9, His-GST)

proteins

Sf9 insect cells

50 μg

720 USD

PFKP protein, central to cellular energy metabolism, catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate, initiating glycolysis. This key enzymatic step regulates glucose entry into glycolysis, initiating essential biochemical reactions for ATP and metabolite generation. PFKP's importance in orchestrating this process highlights its central role in cellular energy homeostasis and broader metabolic regulation. PFKP Protein, Human (sf9, His-GST) is the recombinant human-derived PFKP protein, expressed by Sf9 insect cells , with C-His, N-GST labeled tag. The total length of PFKP Protein, Human (sf9, His-GST) is 784 a.a., with molecular weight of ~113.4 kDa.

Human

The PFKP protein plays a pivotal role in cellular energy metabolism by catalyzing the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate using ATP as a substrate. This enzymatic activity marks the initial and committing step of glycolysis, a fundamental pathway crucial for energy production. Through its catalytic function, PFKP regulates the entry of glucose into glycolysis, initiating a series of biochemical reactions that contribute to the generation of ATP and other essential metabolites. The importance of PFKP in orchestrating this key step underscores its central role in cellular energy homeostasis, emphasizing its significance in the broader context of metabolic regulation.

ATP-dependent 6-phosphofructokinase, platelet type; ATP-PFK; PFK-P; PFK-C; PFKP

Greater than 90% as determined by reducing SDS-PAGE.

Lyophilized from a 0.2 μm filtered solution of 20 mM Tris, 300 mM NaCl, 10% Glycerol, pH 8.0, 0.5 mM TCEP. Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween 80 are added as protectants before lyophilization.

Room temperature in continental US; may vary elsewhere.