protein

PDE3A Protein, Human (sf9, His-GST)

HY-P75961

5 μg;10 μg;50 μg

112;190;528 USD

PDE3A Protein, Human (sf9, His-GST)

Protein

Sf9 insect cells

5 μg;10 μg;50 μg

112;190;528 USD

PDE3A protein, a cyclic nucleotide phosphodiesterase, targets cAMP, cGMP, and cUMP, crucial in diverse physiological processes. In an E2/17beta-estradiol-induced pro-apoptotic pathway, E2 stabilizes the PDE3A/SLFN12 complex, leading to SLFN12 dephosphorylation and activating its pro-apoptotic ribonuclease activity. This pathway is implicated in tissues with high E2 concentrations, potentially contributing to processes like placenta remodeling. PDE3A Protein, Human (sf9, His-GST) is the recombinant human-derived PDE3A protein, expressed by Sf9 insect cells , with N-His, N-GST labeled tag.