protein

NRXN3/Neurexin-3 Protein, Human (HEK293, His)

HY-P75946

5 μg;10 μg;50 μg;100 μg;500 μg;1 mg

35;60;170;290;925;1480 USD

NRXN3/Neurexin-3 Protein, Human (HEK293, His)

proteins

HEK293

5 μg;10 μg;50 μg;100 μg;500 μg;1 mg

35;60;170;290;925;1480 USD

Neurexin-3-beta is neuronal cell surface protein that is involved in cell recognition and cell adhesion. Neurexin-3-beta mediates intracellular signaling. NRXN3/Neurexin-3 Protein, Human (HEK293, His) is the recombinant human-derived NRXN3/Neurexin-3 protein, expressed by HEK293 , with C-His labeled tag. The total length of NRXN3/Neurexin-3 Protein, Human (HEK293, His) is 322 a.a., with molecular weight of 50-60 kDa.

Human

NRXN3 encodes a member of a family of proteins that function in the nervous system as receptors and cell adhesion molecules. Extensive alternative splicing and the use of alternative promoters results in multiple transcript variants and protein isoforms for this gene, but the full-length nature of many of these variants has not been determined. Transcripts that initiate from an upstream promoter encode alpha isoforms, which contain epidermal growth factor-like (EGF-like) sequences and laminin G domains. Transcripts initiating from the downstream promoter encode beta isoforms, which lack EGF-like sequences. Genetic variation at this locus has been associated with a range of behavioral phenotypes, including alcohol dependence and autism spectrum disorder [1] [2] [3] [4] [5] .

Neurexin-3-beta; Neurexin III-beta; NRXN3-CTF; NRXN3; KIAA0743

Greater than 95% as determined by reducing SDS-PAGE

Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.

Room temperature in continental US; may vary elsewhere.