protein

IL-31R alpha Protein, Human (HEK293, Fc)

HY-P75859

2 μg;10 μg;50 μg;100 μg

35;65;170;290 USD

IL-31R alpha Protein, Human (HEK293, Fc)

proteins

HEK293

2 μg;10 μg;50 μg;100 μg

35;65;170;290 USD

IL-31R alpha protein binds to IgM heavy and light chains and helps IgM assembly and secretion. It can act as a molecular chaperone or an oxidoreductase, exhibiting low oxidoreductase activity. IL-31R alpha Protein, Human (HEK293, Fc) is the recombinant human-derived IL-31R alpha protein, expressed by HEK293 , with C-hFc labeled tag.

Human

MZB1/PERP1 associates with immunoglobulin M (IgM) heavy and light chains, facilitating IgM assembly and secretion. It may function as a molecular chaperone or oxidoreductase, as it exhibits a low level of oxidoreductase activity. Additionally, isoform 2 may play a role in apoptosis regulation. MZB1/PERP1 contributes to the diversification of peripheral B-cell functions by modulating Ca(2+) stores, antibody secretion, and integrin activation. Furthermore, it acts as a hormone-regulated adipokine/pro-inflammatory cytokine implicated in chronic inflammation, affecting cellular expansion and attenuating insulin response in adipocytes, potentially playing a role in the onset of insulin resistance.

Interleukin-31 receptor subunit alpha; IL-31R-alpha; IL-31RA; GLM-R; GLM-R; CRL3

Greater than 90% as determined by reducing SDS-PAGE.

Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.

Room temperature in continental US; may vary elsewhere.