protein

IL-18R alpha Protein, Human (HEK293, Fc)

HY-P75842

5 μg;10 μg;50 μg;100 μg

49;84;235;400 USD

IL-18R alpha Protein, Human (HEK293, Fc)

Protein

HEK293

5 μg;10 μg;50 μg;100 μg

49;84;235;400 USD

IL-18R alpha (interleukin-18 receptor alpha) is an interleukin receptor of the immunoglobulin superfamily. IL-18 forms a signalling complex with the IL-18 receptor α (Rα) and β (Rβ) chains at the plasma membrane, which induces multiple inflammatory cytokines. IL-18R complex recruits the IL-1R- activating kinase and TNF- associated factor 6, which phosphorylates nuclear factor kβ- inducing kinase, with subsequent activation of nuclear factor kβ. IL-18R alpha inhibits the production of IFN-γ stimulated with the combination of rhIL-2 and rhIL-18. IL-18R alpha Protein, Human (HEK293, Fc) is a recombinant protein with a Fc label that consists of 329 amino acids (M1-R329) and is produced by HEK293 cells.