protein

GBP2 Protein, Human (HEK293, His)

HY-P75787

5 μg;10 μg;50 μg;100 μg;500 μg

46;75;215;340;950 USD

GBP2 Protein, Human (HEK293, His)

proteins

HEK293

5 μg;10 μg;50 μg;100 μg;500 μg

46;75;215;340;950 USD

CBP2 is an interferon-induced guanylate-binding protein. GBP2 plays an important role in regulating cell proliferation and resisting pathogen infection. p53 can up-regulate GBP2 and play an important role in tumor development by inhibiting metalloproteinases MM9 , NF-Kappa B and Rac proteins. GBP2 Protein, Human (HEK293, His) is the recombinant human-derived GBP2 protein, expressed by HEK293 , with C-His labeled tag.

Human

Interferon is a cytokine that has an antiviral effect and inhibits the proliferation of tumor cells. They induce a large number of genes in target cells, including genes encoding guanylate binding proteins (GBPs). The mouse GBP2 gene is not only highly activated by interferon-gamma during macrophage activation, but also stimulated by toll-like receptors, tumor necrosis factor (TNF), and interleukin-1β. GBP2 plays an important role in regulating cell proliferation and resisting pathogen infection. p53 regulates GBP2 and plays an important role in tumor development by inhibiting metalloproteinases MM9 , NF-Kappa B and Rac proteins [1] [2] [3] .

Guanylate-binding protein 2; GBP-2; HuGBP-2

Greater than 95% as determined by reducing SDS-PAGE

Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4, 8% trehalose.

Room temperature in continental US; may vary elsewhere.