protein

ERAP2 Protein, Human (HEK293, His)

HY-P75756

5 μg;10 μg;50 μg;100 μg

70;110;290;465 USD

ERAP2 Protein, Human (HEK293, His)

proteins

HEK293

5 μg;10 μg;50 μg;100 μg

70;110;290;465 USD

ERAP2 protein, a key aminopeptidase, plays a pivotal role in peptide trimming, crucial for generating peptides binding to HLA class I molecules. By selectively hydrolyzing basic residues like Arginine (Arg) and Lysine (Lys), ERAP2 precisely customizes longer precursor peptides, ensuring optimal length for effective presentation on MHC class I molecules. ERAP2 Protein, Human (HEK293, His) is the recombinant human-derived ERAP2 protein, expressed by HEK293 , with N-His, N-10*His labeled tag. The total length of ERAP2 Protein, Human (HEK293, His) is 905 a.a., with molecular weight of 115-125 kDa.

Human

ERAP2 protein serves as a key aminopeptidase, playing a pivotal role in the crucial process of peptide trimming. This step is essential for the generation of the majority of peptides that bind to HLA class I molecules. By selectively hydrolyzing basic residues such as Arginine (Arg) and Lysine (Lys), ERAP2 contributes to the precise customization of longer precursor peptides, ensuring they attain the appropriate length for effective presentation on MHC class I molecules.

Endoplasmic reticulum aminopeptidase 2; L-RAP; ERAP2; LRAP

Greater than 95% as determined by reducing SDS-PAGE

Supplied as a 0.2 μm filtered solution of 12.5 mM Tris-HCL, 75 mM NaCl, pH 7.5, 50% Glycerol.

Shipping with dry ice