protein

EphB6 Protein, Mouse (HEK293, His)

HY-P75754

2 μg;10 μg;50 μg

35;88;220 USD

EphB6 Protein, Mouse (HEK293, His)

proteins

HEK293

2 μg;10 μg;50 μg

35;88;220 USD

EphB6 Protein, a kinase-defective receptor, binds ephrin-B1 and ephrin-B2, influencing cell adhesion and migration with nuanced effects. Its interaction with ephrin-B2 inhibits JNK activation, T-cell receptor-induced IL-2 secretion, and CD25 expression. EphB6 also interacts with CBL, EPHB1, and ligand-independently with FYN, highlighting its intricate role in cellular signaling pathways. EphB6 Protein, Mouse (HEK293, His) is the recombinant mouse-derived EphB6 protein, expressed by HEK293 , with C-His labeled tag. The total length of EphB6 Protein, Mouse (HEK293, His) is 555 a.a., with molecular weight of ~66 kDa.

Mouse

EphB6, a kinase-defective receptor, serves as a binding partner for members of the ephrin-B family, specifically interacting with ephrin-B1 and ephrin-B2. Its engagement with ephrin-B2 leads to a nuanced modulation of cell adhesion and migration, eliciting both positive and negative effects. EphB6 plays a role in inhibiting JNK activation, T-cell receptor-induced IL-2 secretion, and CD25 expression upon stimulation with ephrin-B2. Furthermore, EphB6 engages in interactions with CBL and EPHB1, and notably associates with FYN in a ligand-independent manner, emphasizing its intricate involvement in cellular signaling pathways.

Ephrin type-B receptor 6; HEP; Tyrosine-protein kinase-defective receptor EPH-6; EPHB9

Greater than 95% as determined by reducing SDS-PAGE

Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.

Room temperature in continental US; may vary elsewhere.