protein

FCAR/CD89 Protein, Rat (HEK293, His)

HY-P75660

5 μg;10 μg;50 μg;100 μg

45;70;180;290 USD

FCAR/CD89 Protein, Rat (HEK293, His)

proteins

HEK293

5 μg;10 μg;50 μg;100 μg

45;70;180;290 USD

FCAR is an Fc fragment of the IgA receptor, also known as CD89. Fcars are found on the cell surface of myeloid cells, including neutrophils, monocytes, macrophages, and eosinophils. FCAR exerts proinflammatory effects by participating in PI3K and PLC-γ signaling. FCAR is also an important Fc receptor for neutrophils to kill tumor cells. FCAR/CD89 Protein, Rat (HEK293, His) is the recombinant rat-derived FCAR/CD89 protein, expressed by HEK293 , with C-His labeled tag. The total length of FCAR/CD89 Protein, Rat (HEK293, His) is 207 a.a., with molecular weight of 35-40 kDa.

Rat

The Fc fragment of the IgA receptor (FCAR) encodes the transmembrane receptor FC-α RI, also known as CD89. Fcars are found on the cell surface of myeloid cells, including neutrophils, monocytes, macrophages, and eosinophils. FCAR plays a role in both pro-inflammatory and anti-inflammatory responses, depending on its binding status to IgA. FCAR exerts proinflammatory effects by participating in PI3K and PLC-γ signaling. FCAR is also an important Fc receptor for neutrophils to kill tumor cells [1] [2] .

Immunoglobulin Alpha Fc Receptor; IgA Fc Receptor; CD89; FCAR

Greater than 95% as determined by reducing SDS-PAGE

Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4. Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween 80 are added as protectants before lyophilization.

Room temperature in continental US; may vary elsewhere.