protein

Fc gamma RIIA/CD32a Protein, Rhesus Macaque (HEK293, His)

HY-P75647

5 μg;10 μg;50 μg;100 μg;500 μg;1 mg

35;60;165;280;810;1380 USD

Fc gamma RIIA/CD32a Protein, Rhesus Macaque (HEK293, His)

proteins

HEK293

5 μg;10 μg;50 μg;100 μg;500 μg;1 mg

35;60;165;280;810;1380 USD

The Fc γ RIIA/CD32a protein plays a key role by specifically binding to the Fc region of immunoglobulin γ, acting as a low-affinity receptor. Fc γ RIIA/CD32a initiates cellular responses against pathogens and soluble antigens and plays an important role in immune regulation. Fc γ RIIA/CD32a interacts with PI3K and Syk. Fc gamma RIIA/CD32a Protein, Rhesus Macaque (HEK293, His) is the recombinant Rhesus Macaque-derived Fc gamma RIIA/CD32a protein, expressed by HEK293 , with C-His labeled tag. The total length of Fc gamma RIIA/CD32a Protein, Rhesus Macaque (HEK293, His) is 184 a.a., with molecular weight of ~25-35 kDa.

Rhesus Macaque

The Fc γ RIIA/CD32a protein plays a key role by specifically binding to the Fc region of immunoglobulin γ, acting as a low-affinity receptor. By interacting with IgG, Fc γ RIIA/CD32a initiates cellular responses against pathogens and soluble antigens, playing an important role in immune regulation. The Fc γ RIIA/CD32a protein promotes the phagocytosis of  sporophoric antigens, further promoting the immune defense mechanism. In addition, Fc γ RIIA/CD32a interacts with IGHG1, INPP5D/SHIP1, INPPL1/SHIP2, APCS, FGR, and HCK to participate in complex signaling pathways and regulate their cellular functions. Fc γ RIIA/CD32a interacts with PI3K and Syk [1] [2] [3] .

Low Affinity Immunoglobulin Gamma Fc Region Receptor II-a; CD32; FCGR2A; FCG2; IGFR2

Greater than 95% as determined by reducing SDS-PAGE

Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.

Room temperature in continental US; may vary elsewhere.