protein

CD164 Protein, Human (HEK293, His)

HY-P75617

5 μg;10 μg;50 μg;100 μg

53;85;240;385 USD

CD164 Protein, Human (HEK293, His)

proteins

HEK293

5 μg;10 μg;50 μg;100 μg

53;85;240;385 USD

CD164 is a sialylamucin that may play a key role in the hematopoietic process, promoting CD34(+) cell adhesion while negatively regulating CD34(+)CD38(lo/-) cell proliferation. It regulates cord blood CD133+ cell migration through the CXCL12/CXCR4 axis and is associated with prostate cancer metastasis and bone marrow invasion. CD164 Protein, Human (HEK293, His) is the recombinant human-derived CD164 protein, expressed by HEK293 , with C-His labeled tag.

Human

CD164 is a sialomucin that potentially holds a pivotal role in hematopoiesis, facilitating the adhesion of CD34(+) cells to the stroma while negatively regulating the proliferation of CD34(+)CD38(lo/-) cells. This protein is implicated in the modulation of umbilical cord blood CD133+ cell migration through the CXCL12/CXCR4 axis. Additionally, CD164 is associated with prostate cancer metastasis and the infiltration of cancer cells into the bone marrow. It exerts a positive influence on myogenesis by enhancing CXCR4-dependent cell motility, promoting myoblast migration, and facilitating myoblast fusion into myotubes. The protein exists as a homodimer (isoform 4) and interacts with CXCR4 in these cellular processes.

Sialomucin core protein 24; MUC-24; Endolyn; MGC-24; CD164

Greater than 95% as determined by reducing SDS-PAGE

Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.

Room temperature in continental US; may vary elsewhere.