protein

Artemin Protein, Mouse (HEK293, Fc)

HY-P75584

2 μg;10 μg;50 μg

42;125;350 USD

Artemin Protein, Mouse (HEK293, Fc)

proteins

HEK293

2 μg;10 μg;50 μg

42;125;350 USD

Artemin Protein, a ligand for GFR-alpha-3-RET and GFR-alpha-1-RET receptor complexes, is vital for the survival of sensory, sympathetic, and dopaminergic neurons. It strongly attracts gut hematopoietic cells, promoting Peyer's patch-like structure formation in the gut-associated lymphoid tissue. Existing in a homodimeric form linked by disulfide bonds, Artemin binds to the RET receptor. Artemin Protein, Mouse (HEK293, Fc) is the recombinant mouse-derived Artemin protein, expressed by HEK293 , with N-hFc labeled tag.

Mouse

Artemin protein functions as a ligand for the GFR-alpha-3-RET receptor complex and can also activate the GFR-alpha-1-RET receptor complex. It plays a vital role in supporting the survival of sensory and sympathetic peripheral neurons in culture and additionally supports the survival of dopaminergic neurons in the ventral mid-brain. Acting as a strong attractant for gut hematopoietic cells, Artemin promotes the formation of Peyer's patch-like structures, which are integral components of the gut-associated lymphoid tissue. The protein exists in a homodimeric form, linked by disulfide bonds, and binds to the RET receptor.

Artemin; ARTN; Enovin; EVN; EVNneurotrophic factor; NBN; Neublastin

Greater than 90% as determined by reducing SDS-PAGE.

Supplied as a 0.22 μm filtered solution of 50mM Glycine,150mM NaCl (pH 3.2).

Shipping with dry ice