protein

ADSL/Adenylosuccinate Lyase Protein, Human (His)

HY-P75565

5 μg;10 μg;50 μg;100 μg;500 μg

55;95;265;450;1260 USD

ADSL/Adenylosuccinate Lyase Protein, Human (His)

proteins

E. coli

5 μg;10 μg;50 μg;100 μg;500 μg

55;95;265;450;1260 USD

ADSL/Adenylosuccinate Lyase Protein catalyzes two non-sequential steps in de novo AMP synthesis. It converts SAICAR to fumarate and 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide, contributing to de novo IMP synthesis. Additionally, it converts succinyladenosine monophosphate (SAMP) to AMP and fumarate. ADSL/Adenylosuccinate Lyase Protein, Human (His) is the recombinant human-derived ADSL/Adenylosuccinate Lyase protein, expressed by E. coli , with N-6*His labeled tag. The total length of ADSL/Adenylosuccinate Lyase Protein, Human (His) is 484 a.a., with molecular weight of ~56 kDa.

Human

ADSL (Adenylosuccinate Lyase) protein serves as the catalyst for two non-sequential steps in de novo AMP synthesis. Firstly, it converts (S)-2-(5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamido)succinate (SAICAR) to fumarate along with 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide, thereby contributing to de novo IMP synthesis. In a separate step, ADSL converts succinyladenosine monophosphate (SAMP) to AMP and fumarate. Through these enzymatic actions, ADSL plays a crucial role in the intricate metabolic pathway leading to the synthesis of adenosine monophosphate (AMP), a fundamental component in nucleotide biosynthesis.

Adenylosuccinate lyase; ADSL; ASL; Asase; AMPS

Greater than 95% as determined by reducing SDS-PAGE

Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4, 10% Glycerol.

Room temperature in continental US; may vary elsewhere.