protein

ACP5 Protein, Human (HEK293, His)

HY-P75561

5 μg;10 μg;50 μg

65;110;300 USD

ACP5 Protein, Human (HEK293, His)

proteins

HEK293

5 μg;10 μg;50 μg

65;110;300 USD

The ACP5 protein actively dephosphorylates osteopontin and bone sialoprotein. Its upregulated expression in pathological conditions like Gaucher and Hodgkin diseases, hairy cell, B-cell, and T-cell leukemias suggests a potential association with these diseases. This underscores ACP5's relevance in diverse pathological states, indicating its role in modulating pathways related to bone health and hematopoietic system disorders. ACP5 Protein, Human (HEK293, His) is the recombinant human-derived ACP5 protein, expressed by HEK293 , with C-His labeled tag. The total length of ACP5 Protein, Human (HEK293, His) is 299 a.a., with molecular weight of ~35 kDa.

Human

The ACP5 protein is actively engaged in the dephosphorylation of osteopontin and bone sialoprotein. Notably, its expression appears to be upregulated in specific pathological conditions, including Gaucher and Hodgkin diseases, as well as hairy cell, B-cell, and T-cell leukemias. This suggests a potential association between ACP5 expression and these pathological states, indicating its relevance in the context of diverse diseases. The involvement of ACP5 in the dephosphorylation of key proteins associated with bone metabolism highlights its role in modulating pathways related to bone health and pathological conditions affecting the hematopoietic system.

Tartrate-resistant acid phosphatase type 5; TR-AP; TrATPase; T5ap; Trap

Greater than 95% as determined by reducing SDS-PAGE

Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.

Room temperature in continental US; may vary elsewhere.