protein

Alanyl-tRNA synthetase Protein, Human (sf9, His)

HY-P75517

5 μg;10 μg;50 μg

43;70;180 USD

Alanyl-tRNA synthetase Protein, Human (sf9, His)

proteins

Sf9 insect cells

5 μg;10 μg;50 μg

43;70;180 USD

The Alanyl-tRNA synthetase protein facilitates a two-step process, activating alanine with ATP to form Ala-AMP and transferring it to the acceptor end of tRNA(Ala). Additionally, it corrects incorrectly charged tRNA(Ala) through its editing domain. Alanyl-tRNA synthetase Protein, Human (sf9, His) is the recombinant human-derived Alanyl-tRNA synthetase protein, expressed by Sf9 insect cells , with N-His labeled tag. The total length of Alanyl-tRNA synthetase Protein, Human (sf9, His) is 968 a.a., with molecular weight of ~109.2 kDa.

Human

Alanyl-tRNA synthetase, a key player in protein synthesis, orchestrates the attachment of alanine to tRNA(Ala) through a meticulous two-step process. Initially, alanine undergoes activation by ATP, leading to the formation of Ala-AMP. Subsequently, this activated alanine is diligently transferred to the acceptor end of tRNA(Ala). Beyond its primary aminoacylation function, Alanyl-tRNA synthetase exhibits a remarkable editing domain, allowing it to rectify incorrectly charged tRNA(Ala). This dual functionality underscores the critical role of Alanyl-tRNA synthetase in maintaining the accuracy and fidelity of the translation process, emphasizing its significance in cellular protein synthesis.

Alanine--tRNA ligase, cytoplasmic; AlaRS; AARS1; AARS

Greater than 90% as determined by reducing SDS-PAGE.

Supplied as a 0.2 μm filtered solution of 20 mM PB, 500 mM NaCl, pH 7.0, 20% Glycerol.

Shipping with dry ice