protein

ANGPTL7/Angiopoietin-related 7 Protein, Rhesus Macaque (HEK293, His)

HY-P75506

2 μg;10 μg;50 μg

35;100;280 USD

ANGPTL7/Angiopoietin-related 7 Protein, Rhesus Macaque (HEK293, His)

proteins

HEK293

2 μg;10 μg;50 μg

35;100;280 USD

ANGPTL7/angiopoietin-related 7 protein plays a crucial role in the formation and organization of the extracellular matrix. Particularly in the eye, it serves as a mediator for dexamethasone-induced matrix deposition within the trabecular meshwork, a tissue that studies have shown is necessary for aqueous humor outflow and maintenance of intraocular pressure. ANGPTL7/Angiopoietin-related 7 Protein, Rhesus Macaque (HEK293, His) is the recombinant Rhesus Macaque-derived ANGPTL7/Angiopoietin-related 7 protein, expressed by HEK293 , with C-His labeled tag.

Rhesus Macaque

The ANGPTL7/Angiopoietin-related 7 protein assumes a crucial role in the formation and organization of the extracellular matrix. Particularly in the eye, it acts as a mediator of dexamethasone-induced matrix deposition within the trabecular meshwork, a tissue essential for the outflow of ocular aqueous humor and the maintenance of intraocular pressure. Additionally, ANGPTL7 serves as a negative regulator of angiogenesis in the cornea, playing a significant role in preserving corneal avascularity and transparency, as suggested by research findings. Structurally, it forms a homotetramer through disulfide linkages, further emphasizing its role in maintaining the structural integrity of the extracellular matrix in ocular tissues.

Angiopoietin like 7; ANGPTL7; CDT6

Greater than 95% as determined by reducing SDS-PAGE.

Lyophilized from a 0.2 μm filtered solution of PBS, pH 6.5, 8% trehalose.

Room temperature in continental US; may vary elsewhere.