protein

BNIP3L Protein, Human

HY-P75471

5 μg;10 μg

60;100 USD

BNIP3L Protein, Human

proteins

E. coli

5 μg;10 μg

60;100 USD

BNIP3L, a pro-apoptotic member of the Bcl-2 family, possesses a BH3 domain and binds to Bcl-2. It directly targets mitochondria, inducing apoptotic changes like membrane potential loss and cytochrome c release. With ubiquitous expression, especially in fat and ovary, the gene suggests involvement in diverse physiological processes across multiple organs, emphasizing its potential significance. BNIP3L Protein, Human is the recombinant human-derived BNIP3L protein, expressed by E. coli , with tag free. The total length of BNIP3L Protein, Human is 186 a.a., with molecular weight of ~32-36 kDa.

Human

The BNIP3L Protein is a member of the pro-apoptotic subfamily within the Bcl-2 family, featuring a BH3 domain and the ability to bind to Bcl-2. This protein exerts its pro-apoptotic effects by directly targeting mitochondria, leading to apoptotic changes such as the loss of membrane potential and the release of cytochrome c. Its role in the regulation of apoptosis suggests its involvement in crucial cellular processes. The gene displaying ubiquitous expression, with prominent levels in fat (RPKM 69.4), ovary (RPKM 49.9), and 24 other tissues, underscores its potential significance in diverse physiological contexts across various organs.

BCL2/adenovirus E1B 19 kDa protein-interacting protein 3-like; NIP3L; BNIP3L; BNIP3A; BNIP3H; NIX

Greater than 90% as determined by reducing SDS-PAGE.

Lyophilized from sterile 50 mM Tris-HCL, 300 mM NaCl, pH 7.4.

Room temperature in continental US; may vary elsewhere.