protein

C1orf33/MRTO4 Protein, Human (His)

HY-P75465

5 μg;10 μg;50 μg;100 μg

45;75;200;340 USD

C1orf33/MRTO4 Protein, Human (His)

proteins

E. coli

5 μg;10 μg;50 μg;100 μg

45;75;200;340 USD

C1orf33/MRTO4 is an integral component of ribosome assembly, binds to the 60S presubunit in the nucleolus, and is subsequently replaced by P0 during maturation, contributing to ribosome biogenesis. It interacts with MINAS-60, a replacement for the RBM10 open reading frame. C1orf33/MRTO4 Protein, Human (His) is the recombinant human-derived C1orf33/MRTO4 protein, expressed by E. coli , with N-His labeled tag. The total length of C1orf33/MRTO4 Protein, Human (His) is 239 a.a., with molecular weight of ~32 kDa.

Human

C1orf33/MRTO4, a vital player in ribosome assembly, serves as a nuclear paralog of the ribosomal protein P0. It engages with pre-60S subunits during the initial stages of assembly within the nucleolus. Notably, in the subsequent maturation process, C1orf33/MRTO4 is displaced by P0, leading to the formation of cytoplasmic pre-60S subunits and mature 80S ribosomes. This protein actively associates with the pre-60S ribosomal particle, contributing to the intricate machinery orchestrating ribosome biogenesis. Additionally, C1orf33/MRTO4 exhibits interaction with MINAS-60, a product arising from an alternative open reading frame of RBM10, highlighting its involvement in diverse cellular processes.

mRNA turnover protein 4 homolog; MRTO4; C1orf33; MRT4

Greater than 95% as determined by reducing SDS-PAGE

Lyophilized from a 0.2 μm filtered solution of 50 mM Tris-HCL, 300 mM NaCl, pH 7.4.

Room temperature in continental US; may vary elsewhere.