protein

Apolipoprotein M/APOM Protein, Human (166a.a, HEK293, His)

HY-P7536A

5 μg;10 μg;50 μg;100 μg;250 μg;500 μg;1 mg

53;85;240;385;690;1050;1650 USD

Apolipoprotein M/APOM Protein, Human (166a.a, HEK293, His)

proteins

HEK293

5 μg;10 μg;50 μg;100 μg;250 μg;500 μg;1 mg

53;85;240;385;690;1050;1650 USD

Apolipoprotein M Protein, Human (166a.a, HEK293, His) expresses in HEK293, does not contain signal peptide sequence with a His tag at the N-terminus. Apolipoprotein E (apoE) secreted by HEK cells stably expressing apoE3 or apoE4 (HEK-apoE) binds Aβ, and inhibits Aβ-induced neurotoxicity [1] .

Human

Apolipoprotein E (apoE) is a 34-kDa glycoprotein that is a surface component of various plasma lipoprotein particles including chlyomicron remnants, β-migrating VLDL (β-VLDL), LDL, and a subclass of HDL. ApoE mediates high-affinity binding of apoE-containing lipoproteins to cell surface endocytic receptors during the transport and metabolism of plasma cholesterol (Chol) and triglycerides (TG). HEK-apoE is a ligand for low-density lipoprotein (LDL) receptor-related protein (LRP) but not the LDL receptor [1] .

rHuApolipoprotein M, His; ApoM; Apolipoprotein M

Greater than 90% as determined by reducing SDS-PAGE

Lyophilized after extensive dialysis against PBS, pH 7.4.

Room temperature in continental US; may vary elsewhere.