protein

CG alpha Protein, Human (HEK293)

HY-P75342

2 μg;10 μg;50 μg;100 μg

45;125;350;595 USD

CG alpha Protein, Human (HEK293)

proteins

HEK293

2 μg;10 μg;50 μg;100 μg

45;125;350;595 USD

CG alpha, a glycoprotein hormone subunit, contributes to chorionic gonadotropin, luteinizing hormone, follicle-stimulating hormone, and thyroid-stimulating hormone. While alpha subunits are identical, beta chains confer specificity. Encoded by this gene, CG alpha belongs to the glycoprotein hormones alpha chain family. Restrictedly expressed in the placenta (RPKM 388.3). Two transcript variants exist. CG alpha Protein, Human (HEK293) is the recombinant human-derived CG alpha protein, expressed by HEK293 , with tag free. The total length of CG alpha Protein, Human (HEK293) is 92 a.a., with molecular weight of ~11.86 & 15-22 kDa, respectively.

Human

CG alpha Protein, the encoded alpha subunit of the human glycoprotein hormones, including chorionic gonadotropin (CG), luteinizing hormone (LH), follicle-stimulating hormone (FSH), and thyroid-stimulating hormone (TSH), plays a pivotal role in forming noncovalent dimers with beta subunits, conferring biological specificity to each hormone. While the alpha subunits are identical across these hormones, their unique beta chains determine their distinct functions. CG alpha belongs to the glycoprotein hormones alpha chain family and is expressed predominantly in the placenta (RPKM 388.3). The restricted expression pattern highlights its specialization in placental tissues, where it contributes to the regulatory functions of glycoprotein hormones crucial for reproductive and endocrine processes. Two transcript variants, encoding different isoforms, have been identified for this gene, adding to the complexity of its regulatory mechanisms in various physiological contexts.

Glycoprotein hormones alpha chain; CG-alpha; FSH-alpha; CGA

Greater than 90% as determined by reducing SDS-PAGE.

Lyophilized from a 0.2 μm filtered solution of 20 mM PB, 150 mM NaCl, pH 7.4.

Room temperature in continental US; may vary elsewhere.