protein

Apolipoprotein A-II/APOA2 Protein, Human (HEK293, His)

HY-P7527

10 μg;50 μg

179;500 USD

Apolipoprotein A-II/APOA2 Protein, Human (HEK293, His)

proteins

HEK293

10 μg;50 μg

179;500 USD

406168020

Apolipoprotein A-II/ApoA2 Protein, Human (HEK293, His) expresses in HEK293 with a His tag at the N-terminus. Apolipoprotein A-II (ApoA-II) has been associated with numerous aspects of HDL metabolism, and apoA-II overexpression produces the proatherogenic phenotype [1] .

Human

Recombinant apoA-II is comparable to the plasma form in its ability to bind and reorganize lipid and promote cholesterol efflux from macrophages via the ATP binding cassette transporter A1. Synthesized primarily in the liver, apoA-II is a 77 amino acid protein with a single cysteine at position. In healthy humans, apoA-II exists almost entirely as a disulfide-linked homodimer (molecular mass, 17.4 kDa), though it can be occasionally found as a heterodimer with other Cys-containing proteins [1] .

rHuApolipoprotein A-II, His; ApoA2; Apolipoprotein A-II

Greater than 95% as determined by reducing SDS-PAGE.

Lyophilized from a 0.2 μm filtered solution of 20 mM PB, 150 mM NaCl, pH 7.4.

Room temperature in continental US; may vary elsewhere.