protein

Ebola virus Glycoprotein/GP Protein (QDA39862, HEK293, His)

HY-P75268

5 μg;10 μg;20 μg;50 μg

72;115;185;350 USD

Ebola virus Glycoprotein/GP Protein (QDA39862, HEK293, His)

Protein

HEK293

5 μg;10 μg;20 μg;50 μg

72;115;185;350 USD

Ebola virus Glycoprotein/GP Protein is pivotal in viral entry, serving as the receptor-binding subunit.In later infection stages, GP1 down-regulates crucial host cell surface molecules, including integrins like ITGA1-6, disrupting adhesion and potentially causing blood vessel integrity disruption.GP1 interacts with host TLR4, stimulating monocyte differentiation, leading to T-lymphocyte bystander death.It down-regulates natural killer cell function, counters BST2/tetherin, cooperates with VP40 for NF-kappa-B activation, acts as an antibody decoy, and induces cytokine transcription in host macrophages and dendritic cells through TLR4 activation.Ebola virus Glycoprotein/GP Protein (QDA39862, HEK293, His) is the recombinant Virus-derived Ebola virus Glycoprotein/GP protein, expressed by HEK293 , with C-His labeled tag.