protein

ECM1 Protein, Rat (HEK293, His)

HY-P75264

5 μg;10 μg;50 μg;100 μg

72;115;300;480 USD

ECM1 Protein, Rat (HEK293, His)

proteins

HEK293

5 μg;10 μg;50 μg;100 μg

72;115;300;480 USD

The ECM1 protein is a multifaceted player that negatively regulates bone mineralization and affects endochondral bone formation. In addition to bone biology, it stimulates endothelial cell proliferation and angiogenesis and exerts regulatory control on MMP9 proteolytic activity. ECM1 Protein, Rat (HEK293, His) is the recombinant rat-derived ECM1 protein, expressed by HEK293 , with C-His labeled tag. The total length of ECM1 Protein, Rat (HEK293, His) is 543 a.a., with molecular weight of 75-80 kDa.

Rat

ECM1 protein emerges as a multifaceted participant in cellular processes, particularly influencing endochondral bone formation by acting as a negative regulator of bone mineralization. Beyond its role in bone biology, ECM1 extends its influence to endothelial cells, where it stimulates proliferation and fosters angiogenesis. Notably, it exercises regulatory control over MMP9 proteolytic activity, contributing to the intricate balance of molecular events. In its functional repertoire, ECM1 engages in molecular interactions, forming associations with HSPG2, EFEMP1/FBLN3, LAMB3, and MMP9, thereby participating in a network of molecular relationships that underscore its significance in diverse cellular contexts.

Extracellular matrix protein 1; Secretory component p85; Ecm1

Greater than 95% as determined by reducing SDS-PAGE.

Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.

Room temperature in continental US; may vary elsewhere.