protein

FDPS Protein, Mouse (His)

HY-P75196

5 μg;10 μg

50;80 USD

FDPS Protein, Mouse (His)

proteins

E. coli

5 μg;10 μg

50;80 USD

FDPS proteins are key enzymes in isoprenoid biosynthesis and play a crucial role in the formation of farnesyl diphosphate (FPP). FPP is a precursor of essential metabolites involved in protein farnesylation and geranylgeranylation. FDPS Protein, Mouse (His) is the recombinant mouse-derived FDPS protein, expressed by E. coli , with N-His labeled tag. The total length of FDPS Protein, Mouse (His) is 353 a.a., with molecular weight of ~42.8 kDa.

Mouse

Farnesyl diphosphate synthase (FDPS) emerges as a pivotal enzyme in isoprenoid biosynthesis, driving the crucial formation of farnesyl diphosphate (FPP). FPP, a key precursor for various essential metabolites such as sterols, dolichols, carotenoids, and ubiquinones, also serves as a substrate for protein farnesylation and geranylgeranylation. The catalytic activity of FDPS involves the sequential condensation of isopentenyl pyrophosphate with the allylic pyrophosphates, first with dimethylallyl pyrophosphate and then with the resulting geranylpyrophosphate, ultimately yielding the essential product, farnesyl pyrophosphate. This intricate enzymatic process underscores FDPS's central role in the synthesis of fundamental cellular components and post-translational modifications critical for diverse cellular functions.

Farnesyl pyrophosphate synthase; FPP synthase; CR 39; Fdps

Greater than 95% as determined by reducing SDS-PAGE.

Lyophilized from a 0.2 μm filtered solution of 50 mM Tris-HCL, 300 mM NaCl, pH 8.0.

Room temperature in continental US; may vary elsewhere.