protein

Flagellin Protein, Listeria monocytogenes (His)

HY-P75185

20 μg;100 μg

220;600 USD

Flagellin Protein, Listeria monocytogenes (His)

proteins

E. coli

20 μg;100 μg

220;600 USD

Flagellin Protein is the subunit protein which polymerizes to form the filaments of bacterial flagella.It is a natural immune agonist that activates innate immunity and then stimulates the adaptive immune response.Flagellin directly activates a number of immune and non-immune cells through TLR5.In addition, it has anti-tumor and radioprotective activity and shows great potential in combating tumor growth and radiation-related tissue damage. Flagellin Protein, Listeria monocytogenes (His) is the recombinant Flagellin protein, expressed by E.coli , with N-His labeled tag.

Others

Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella. Flagellin is a natural immune agonist that activates innate immunity and then stimulates the adaptive immune response. It is expressed in many types of immune cells, including epithelial cells, polymorphonuclear neutrophils, natural killer (NK) cells, myeloid dendritic cells (mDCs), monocytes, Langerhans cells, macrophages and T cells. Flagellin, as an adjuvant, can induce an enhanced antigen-specific immune response. Flagellin directly activates a number of immune and non-immune cells, including T, B, DCs, NK and non-lymphoid cells (macrophages, epithelial, fibroblasts, stromal cells and neutrophils), through TLR5. The cumulative effect of this activation is the augmentation of immune responses through the generation of more potent antibodies and a Th1 response. In addition, it has anti-tumor and radioprotective activity and shows great potential in combating tumor growth and radiation-related tissue damage [1] [2] .

Listeria monocytogenes flaA Protein; flaA

Greater than 95% as determined by reducing SDS-PAGE

Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4. Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween 80 are added as protectants before lyophilization.

Room temperature in continental US; may vary elsewhere.