protein

FUT8 Protein, Human (sf9, His)

HY-P75181

5 μg;10 μg;20 μg;50 μg

138;235;400;658 USD

FUT8 Protein, Human (sf9, His)

proteins

Sf9 insect cells

5 μg;10 μg;20 μg;50 μg

138;235;400;658 USD

The FUT8 protein acts as a catalyst during glycosylation, specifically adding fucose in an α1-6 linkage to the first GlcNAc residue located near the N-glycan peptide chain. This enzymatic activity plays a crucial role in glycoprotein modification, contributing to the structural diversity and functional properties of N-glycans. FUT8 Protein, Human (sf9, His) is the recombinant human-derived FUT8 protein, expressed by Sf9 insect cells , with C-His labeled tag.

Human

FUT8, or alpha-1,6-fucosyltransferase 8, is an enzyme that plays a key role in glycosylation processes by catalyzing the addition of fucose in an alpha 1-6 linkage to the initial GlcNAc residue adjacent to peptide chains in N-glycans. This enzymatic activity is crucial for the modification of glycoproteins, influencing their structure and function. By specifically adding fucose in this alpha 1-6 linkage, FUT8 contributes to the diverse repertoire of glycan structures, impacting cellular recognition, signaling, and other essential biological processes. It has to highlight FUT8's specificity in glycan modification, shedding light on its role in shaping the glycoproteome and participating in various cellular functions influenced by glycosylation.

Alpha-(1,6)-fucosyltransferase; Alpha1-6FucT; FUT8; Fucosyltransferase 8

Greater than 95% as determined by reducing SDS-PAGE.

Supplied as a 0.2 μm filtered solution of 20 mM Tris, 500 mM NaCl, pH 8.0, 10% gly.

Shipping with dry ice.