protein

GAD2/GAD65 Protein, Mouse (sf9)

HY-P75178

5 μg;10 μg;50 μg;100 μg

65;105;300;480 USD

GAD2/GAD65 Protein, Mouse (sf9)

proteins

Sf9 insect cells

5 μg;10 μg;50 μg;100 μg

65;105;300;480 USD

GAD2/GAD65 Protein is a key enzyme in neurotransmitter metabolism, specifically catalyzing the production of gamma-aminobutyric acid (GABA). Meanwhile, GAD2 also has glutamate binding activity, glutamate decarboxylase activity, and pyridoxal phosphate binding activity. GAD2 is expressed in several structures, including the genitourinary system, the gastrointestinal nervous system, and sensory organs. It can be used to study epilepsy and type 1 diabetes. GAD2/GAD65 Protein, Mouse (sf9) is the recombinant mouse-derived GAD2/GAD65 protein, expressed by Sf9 insect cells , with tag free. The total length of GAD2/GAD65 Protein, Mouse (sf9) is 585 a.a., with molecular weight of ~58 kDa.

Mouse

Glutamate decarboxylase 2 (GAD2) is a key enzyme in neurotransmitter metabolism, specifically catalyzing the production of gamma-aminobutyric acid (GABA). GABA is a crucial inhibitory neurotransmitter in the central nervous system, playing a pivotal role in regulating neuronal excitability and maintaining the balance between excitation and inhibition in the brain. As the catalyst for GABA synthesis, GAD2 plays a fundamental role in modulating neurotransmission and influencing various physiological processes, highlighting its importance in the intricate network of neural signaling within the nervous system. Meanwhile, GAD2 also has glutamate binding activity, glutamate decarboxylase activity, and pyridoxal phosphate binding activity. GAD2 is expressed in several structures, including the genitourinary system, the gastrointestinal nervous system, and sensory organs. In addition, GAD2 can be used to study epilepsy and type 1 diabetes [1] .

Glutamate decarboxylase 2; GAD-65; GAD2

Greater than 90% as determined by reducing SDS-PAGE

Supplied as a 0.2 μm filtered solution of 50 mM Tris, 100 mM NaCl, 10% Glycerol, 3 mM DTT, pH 8.0.

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