protein

GAS6 Protein, Mouse (HEK293, His)

HY-P75174A

5 μg;10 μg;50 μg;100 μg

52;90;250;420 USD

GAS6 Protein, Mouse (HEK293, His)

proteins

HEK293

5 μg;10 μg;50 μg;100 μg

52;90;250;420 USD

GAS6 Protein is a vitamin K-dependent protein involved in signaling pathways including GAS6/AXL. The GAS6 Protein contains an NH 2 terminal Gla domain as well as four EGF-like repeats and tandem gl bular domains. GAS6 Protein, Mouse (674a.a, HEK293, His) is the recombinant mouse-derived GAS6 protein, expressed by HEK293 , with C-His labeled tag.

Mouse

Growth arrest specific protein 6 (GAS6) is a vitamin K-dependent protein that has a high degree of structural homology with natural anticoagulant S, having the same modular composition and 40% sequence homology. GAS6 contains an NH 2 terminal Gla domain as well as four EGF-like repeat sequences and tandem globular domains. GAS6 is a ligand for the tyrosine-protein kinase receptors AXL, TYRO3, and MER, whose signaling is involved in cell growth and survival, cell adhesion, and cell migration. GAS6/AXL signaling plays a role in a variety of processes, such as the survival of endothelial cells during acidification, by preventing apoptosis, optimal cytokine signaling during human natural killer cell development, liver regeneration, survival and migration of gonadotropin-releasing hormone neurons, platelet activation or regulation of thrombotic response [1] [2] [3] [4] [5] .

AXLLG; AXSFAXL receptor tyrosine kinase ligand; GAS-6

Greater than 95% as determined by reducing SDS-PAGE.

Lyophilized from a 0.22 μm filtered solution of PBS, pH 7.4.

Room temperature in continental US; may vary elsewhere.