protein

Annexin A5/ANXA5 Protein, Human (solution)

HY-P7517

10 μg;50 μg

115;320 USD

Annexin A5/ANXA5 Protein, Human (solution)

proteins

E. coli

10 μg;50 μg

115;320 USD

Annexin A5 Protein, Human is a 35 kDa multifunctional protein which belongs to the annexin family. Annexin A5 induces in vitro fusion and aggregation of vesicles in a Ca 2+ - and acidic-pH-dependent manner.Annexin A5 is accepted as an early marker of apoptosis. Annexin A5 has anti-thrombotic and anti-microbial properties [1] .

Human

The Annexins comprise a family of proteins that are involved in many aspects of cellular membrane dynamics and the regulation of membrane-associated proteins. Recombinant Human Annexin A5 is a Ca 2+ -sensitive protein that binds to negatively charged phospholipids, establishing specific interactions with other lipid microdomains [1] . Recombinant Human Annexin A5 promotes delivery of autophagosomes to lysosomes and inhibits endocytosis. Annexin A5 emerges as a possible positive regulator of autophagy and negative regulator of endocytosis through Ca 2+ and phospholipid signalling pathways [1] [1] .

rHuAnnexin A5; ANXA5; Annexin A5; Annexin V; Calphobindin I (CPB-I); Endonexin II; Anchorin CII; ANX5; ENX2; PP4

Greater than 95% as determined by reducing SDS-PAGE.

Supplied as a 0.2 μm filter solution of 20 mM Tris-HCl, 1 mM DTT, 10% Glycerol, pH 8.0.

Shipping with dry ice.