protein

HCMV Glycoprotein B/gB Protein (HEK293, Fc)

HY-P75161

5 μg;10 μg;50 μg

60;100;280 USD

HCMV Glycoprotein B/gB Protein (HEK293, Fc)

proteins

HEK293

5 μg;10 μg;50 μg

60;100;280 USD

The gB Protein is an envelope glycoprotein that plays a role in host cell entry, cell-to-cell viral transmission, and infected cell fusion.gB Protein interacts with heparin sulfate proteoglycan and forms an association with gH/gL heterodimer.HCMV Glycoprotein B/gB Protein (HEK293, Fc) is a recombinant Virus-derived HCMV Glycoprotein B/gB protein(with cleavage site mutated RTKR to TTQT), expressed by HEK293 , with C-hFc labeled tag.HCMV Glycoprotein B/gB Protein (HEK293, Fc), has molecular weight of 160-170 kDa.

Virus

gB is an envelope glycoprotein that plays a role in host cell entry, cell-to-cell viral transmission, and infected cell fusion. gB is involved in initial attachment through a gM/gN complex bound to heparin sulfate, which binds heparin with higher affinity. gB plays a key role in the fusion of viruses and cell membranes, facilitating the entry of viruses into host cells. The complex fusion mechanisms required for this process include at least gB and gH/gL heterodimers. gB interacts with host integrins ITGB1, PDGFRA, and EGFR, possibly entering the receptor as post-attachment [1] [2] [3] .

Human cytomegalovirus (HCMV) Glycoprotein B / gB Protein; Envelope glycoprotein B; UL55

Greater than 80% as determined by reducing SDS-PAGE.

Supplied as a 0.2 μm filtered solution of 100 mM Glycine, 10 mM NaCl, 50 mM Tris, pH 7.5.

Shipping with dry ice