protein

ANGPTL3/Angiopoietin-like 3 Protein, Mouse (HEK293, His)

HY-P7504

10 μg;50 μg

125;320 USD

ANGPTL3/Angiopoietin-like 3 Protein, Mouse (HEK293, His)

proteins

HEK293

10 μg;50 μg

125;320 USD

406168010

ANGPTL3/Angiopoietin-like 3 Protein, Mouse (HEK293, His) is a mouse recombinant ANGPTL3 with a 10-His tag at the C-terminus. Angiopoietin-like Protein 3, Mouse (HEK293, His) is produced by Mammalian expression system and the target gene encoding Ser17-Thr455 is expressed.

Mouse

ANGPTL3/Angiopoietin-like 3 Protein is a 70 kDa 460-amino acid long secretory glycoprotein primarily expressed in the liver. Mature mouse ANGPTL3 contains an N-terminal coiled-coil domain and a C-terminal fibrinogen-like domain. ANGPTL3 is implicated in angiogenesis and atherogenesis. ANGPTL3 can regulate serum lipid levels by acting on lipoprotein lipase- (LPL-) and endothelial lipase- (EL-) mediated triglyceride (TG) and phospholipid hydrolysis. Serum ANGPTL3 levels could serve as a biomarker for future occurrence of major adverse cardiovascular events (MACEs) with coronary artery disease (CAD). ANGPTL3 acts as proangiogenic and could induce angiogenesis in vivo via binding of the C-terminal fibrinogen-like domain to the integrin αvβ3 receptor on vascular endothelial cells [1] .

rMuAngiopoietin-like Protein 3, His; ANGPTL3; Angiopoietin-like Protein 3

Greater than 95% as determined by reducing SDS-PAGE.

Lyophilized after extensive dialysis against PBS, pH 7.4.

Room temperature in continental US; may vary elsewhere.