protein

Amyloid Precursor Protein, Human (HEK293, Fc)

HY-P7501

10 μg;50 μg

170;480 USD

Amyloid Precursor Protein, Human (HEK293, Fc)

proteins

HEK293

10 μg;50 μg

170;480 USD

Amyloid Precursor Protein, Human (HEK293, Fc) is an Amyloid Precursor (APP) protein with C-Fc. Amyloid Precursor Protein can be used for the study of brain development, learning and memory, synaptic plasticity, and neurodegeneration [1] .

Human

Recombinant Human Amyloid Precursor is a single-pass transmembrane protein expressed at high levels in the brain and metabolized in a rapid and highly complex fashion by a series of sequential protease, including the intramembranous γ-secretase complex. Human Amyloid Precursor is a disulfide-linked homodimeric protein after removal of the signal peptide, it modulates cell growth, motility, neurite outgrowth, and cell survival, functions that can be reproduced by the soluble ectodomain, which is released by cleavage of APP. Human Amyloid Precursor protein and amyloid beta alter bioenergetic pathways and mitochondrial function [1] [2] .

rHuAmyloid Precursor, C-Fc; Amyloid-Precursor

Greater than 95% as determined by reducing SDS-PAGE.

Lyophilized after extensive dialysis against PBS, pH 7.4.

Room temperature in continental US; may vary elsewhere.