protein

AIF1 Protein, Human (N-His)

HY-P7488A

2 μg;10 μg;50 μg;100 μg

57;160;490;820 USD

AIF1 Protein, Human (N-His)

proteins

E. coli

2 μg;10 μg;50 μg;100 μg

57;160;490;820 USD

The AIF1 protein is an actin-binding promoter that enhances membrane ruffling, activates RAC, and amplifies the actin-bundling activity of LCP1. This calcium-binding protein has a critical impact on RAC signaling, phagocytosis, and may contribute to macrophage function. AIF1 Protein, Human (N-His) is the recombinant human-derived AIF1 protein, expressed by E. coli , with N-His labeled tag. The total length of AIF1 Protein, Human (N-His) is 147 a.a., with molecular weight of ~19 kDa.

Human

AIF1, an actin-binding protein, serves as a facilitator of membrane ruffling and RAC activation, and augments the actin-bundling activity of LCP1. This calcium-binding protein plays a crucial role in RAC signaling, phagocytosis, and potentially contributes to macrophage activation and function. AIF1 is implicated in promoting the proliferation of vascular smooth muscle cells and T-lymphocytes, as well as enhancing lymphocyte migration. Additionally, it is involved in vascular inflammation. AIF1 can exist as a homodimer (Potential) or a monomer and interacts with LCP1, indicating its participation in intricate molecular interactions governing cellular processes.

AIF-1; Allograft inflammatory factor 1

Greater than 95% as determined by reducing SDS-PAGE.

Lyophilized from a 0.2 μm filtered solution of 50 mM Tris, 300 mM NaCl, 5% trehalose, 5% mannitol and 0.01% Tween80, pH 7.4.

Room temperature in continental US; may vary elsewhere.