protein

envelope glycoprotein gp160 Protein, HIV-1 (AAT67478, HEK293, His)

HY-P74885

5 μg;10 μg;50 μg

78;125;350 USD

envelope glycoprotein gp160 Protein, HIV-1 (AAT67478, HEK293, His)

proteins

HEK293

5 μg;10 μg;50 μg

78;125;350 USD

gp160 is an envelope glycoprotein that oligomerizes into major trimers in the host endoplasmic reticulum.gp160 is transported in the host Golgi apparatus to complete the glycosylation process.The precursors are proteolytic cleaved in the trans-Golgi apparatus to produce gp120 and gp41.envelope glycoprotein gp160 Protein, HIV-1 (AAT67478, HEK293, His) is the recombinant Virus-derived envelope glycoprotein gp160 protein, expressed by HEK293 , with C-His labeled tag.

Virus

gp160 is an envelope glycoprotein that oligomerizes into major trimers in the host endoplasmic reticulum. gp160 is transported in the host Golgi apparatus to complete the glycosylation process. The precursor is proteolytically cleaved in the trans-Golgi apparatus and thus activated by cellular furin or Furin-like proteases to produce surface gp120 and transmembrane protein gp41. The sequential binding of gp120 to receptors (CD4) and co-receptors (such as CCR5 or CXCR4) triggers large conformational changes in gp120 and gp41, leading to fusion and viral entry [1] [2] .

HIV-1 (group M, subtype A, isolate 92RW020) Envelope glycoprotein gp160 Protein (gp120 subunit) (His)

Greater than 85% as determined by reducing SDS-PAGE.

Supplied as a 0.2 μm filtered solution of PBS, pH 7.4.

Shipping with dry ice