protein

IGFBP-2 Protein, Mouse (HEK293, His)

HY-P74846

20 μg;50 μg

183;400 USD

IGFBP-2 Protein, Mouse (HEK293, His)

proteins

HEK293

20 μg;50 μg

183;400 USD

IGFBP-2 protein, a member of the IGF-binding protein family, inhibits IGF-mediated growth and developmental rates. It can extend the half-life of IGF and exhibit dual functions by inhibiting or stimulating the growth-promoting effect of IGF in cell culture. IGFBP-2 Protein, Mouse (HEK293, His) is the recombinant mouse-derived IGFBP-2 protein, expressed by HEK293 , with C-His labeled tag. The total length of IGFBP-2 Protein, Mouse (HEK293, His) is 271 a.a., with molecular weight of ~32-40 kDa.

Mouse

IGFBP-2 protein acts as an inhibitor, specifically targeting IGF-mediated growth and developmental rates. As a member of the IGF-binding protein family, IGFBP-2 prolongs the half-life of IGFs and exhibits dual functionality, either inhibiting or stimulating the growth-promoting effects of IGFs in cell culture. This modulation occurs through the alteration of the interaction between IGFs and their cell surface receptors. Notably, IGFBP-2 demonstrates a higher binding affinity for IGF2 compared to IGF1, underscoring its role in finely regulating the intricate balance of IGF signaling pathways.

IBP-2; Insulin-like growth factor binding protein 2; IGFBP2; IGF-BP53

Greater than 95% as determined by Tris-Bis PAGE

Lyophilized a 0.2 μm filtered solution of PBS, pH 7.4. Normally 8% trehalose is added as protectant before lyophilization.

Room temperature in continental US; may vary elsewhere.