protein

IGFBP-7 Protein, Mouse (HEK293, Fc)

HY-P74844

2 μg;5 μg;10 μg;50 μg;100 μg

35;66;105;210;340 USD

IGFBP-7 Protein, Mouse (HEK293, Fc)

proteins

HEK293

2 μg;5 μg;10 μg;50 μg;100 μg

35;66;105;210;340 USD

IGFBP-7 Protein is a member of the insulin-like growth factor binding protein (IGFBP) Family. The major function of IGFBP-7 is the regulation of availability of insulin-like growth factors (IGFs) in tissue as well as in modulating IGF binding to its receptors. IGFBP7 exhibits a relatively low affinity for binding to both IGF-I and IGF-II. Furthermore, it has the capacity to stimulate the production of prostacyclin (PGI2) and enhance cell adhesion. IGFBP-7 Protein, Mouse (HEK293, Fc) is the recombinant mouse-derived IGFBP-7 protein, expressed by HEK293 , with C-hFc labeled tag. The total length of IGFBP-7 Protein, Mouse (HEK293, Fc) is 256 a.a., with molecular weight of ~53.3-60 kDa.

Mouse

Insulin-like growth factor binding protein 7 (IGFBP-7) is a member of the IGFBP Family. IGFBP-7 is high expressed in liver, kidney, bone and muscle, and the expression level is higher in renal tubules. IGFBP7 exhibits a relatively low affinity for binding to both IGF-I and IGF-II compared to IGFBPs 1-6. Furthermore, it has the capacity to stimulate the production of prostacyclin (PGI2) and enhance cell adhesion. IGFBP-7 interacts with Insulin-like growth factor 1, VPS24, and the IGF-1 receptor. Its wider distribution in normal tissue and lower expression in several cancer cells indicate that IGFBP-7 may function as a growth-suppressing factor, as well as an IGF-binding protein [1] [2] [3] .

IBP-7; IGFBP7; IGFBP-7v; Insulin-like growth factor binding protein 7

Greater than 95% as determined by reducing SDS-PAGE.

Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.

Room temperature in continental US; may vary elsewhere.