product summary
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company name :
MedChem Express LLC
product type :
protein
product name :
BMPR1A/ALK-3 Protein, Human (HEK293, Fc-His)
catalog :
HY-P7484
quantity :
10 μg;50 μg
price :
55;150 USD
product information
Catalog Number :
HY-P7484
Product Name :
BMPR1A/ALK-3 Protein, Human (HEK293, Fc-His)
Product Type :
Protein
Host Species :
HEK293
Size :
10 μg;50 μg
List Price :
55;150 USD
Product Description :
BMPR1A/ALK-3 protein (ACVRLK3) is the receptor bone morphogenetic protein (BMP) type I receptors, widely expressed in tissues. BMPR1A/ALK-3 protein mediates iron metabolism factor hepcidin expression, interacts with GDF5/6 to regulate chondrocyte differentiation and adipogenesis. BMPR1A-ID2/ZEB1-TGFBR2 signaling axis could serve as a potentia target for pulmonary arterial hypertension (PAH) and other endothelial-mesenchymal transition (EndoMT)-related vascular disorders. Human BMPR1A/ALK-3 has a full length of 532 a.a., with a motif (107-109 a.a.) mediating specificity for BMP ligand. BMPR1A/ALK-3 Protein, Human (HEK293, Fc-His) is produced in HEK293 cells and has 129 amino acids (Q24-R152), with C-terminal Fc and His-tags.
company information
MedChem Express LLC
18 Wilkinson Way, Princeton, NJ 08540
sales@medchemexpress.com
http://www.medchemexpress.com
609-228-6898
headquarters: USA