ALDH1A2 Protein, Human (His) | MedChem Express LLC HY-P7475 product information

product summary

company name :

MedChem Express LLC

product type :

protein

product name :

ALDH1A2 Protein, Human (His)

catalog :

HY-P7475

quantity :

10 μg;50 μg

price :

140;360 USD

more info or order :

MedChem Express LLC product webpage

product information

Catalog Number :

HY-P7475

Product Name :

ALDH1A2 Protein, Human (His)

Product Type :

proteins

Host Species :

E. coli

Size :

10 μg;50 μg

List Price :

140;360 USD

list of Pubmed id :

406167993

Product Description :

ALDH1A2 Protein, Human (His) is a human recombinant ALDH1A2 with a N-terminal His tag produced in E. coli. ALDH1A2 Protein, Human (His) expresses the target gene encoding Met1-Ser518.

SpeciesSummary :

Human

Background :

The aldehyde dehydrogenase 1 (ALDH1) family comprises major enzymes that produce retinoic acid (RA) via the oxidation of all-trans retinal and 9-cis-retinal. The ALDH1A subfamily consists of three members, ALDH1A1, ALDH1A2, and ALDH1A3. ALDH1A2 is a rate-limiting enzyme involved in the cellular synthesis of retinoic acid, which has prodifferentiation properties. ALDH1A2 is a candidate tumor suppressor. Low ALDH1A2 expression was associated with an unfavorable prognosis in head and neck squamous cell carcinoma. ALDH1A2 suppresses epithelial ovarian cancer cell proliferation and migration by downregulating STAT3 [1] [2] .

ALTnames :

rHuAldehyde Dehydrogenase 1-A2, His ; ALDH-1A2; Aldehyde Dehydrogenase 1-A2

Purity :

Greater than 90% as determined by reducing SDS-PAGE.

Buffer :

Supplied as a 0.2 μm filter solution of 20 mM Tris-HCl, 150 mM NaCl, 20% Glycerol, pH 7.5.

Storage :

Shipping with dry ice

more info or order :

MedChem Express LLC product webpage