protein

MMP-12 Protein, Human

HY-P74744

20 μg;100 μg

240;660 USD

MMP-12 Protein, Human

proteins

E. coli

20 μg;100 μg

240;660 USD

MMP-12 protein is potentially engaged in tissue injury and remodeling, displaying significant elastolytic activity. It shows flexibility at the P1' site, accommodating both large and small amino acids, yet favoring leucine. At the P1 site, it prefers aromatic or hydrophobic residues, with a tendency for small hydrophobic residues like alanine in the P3 position. MMP-12 Protein, Human is the recombinant human-derived MMP-12 protein, expressed by E. coli , with tag free. The total length of MMP-12 Protein, Human is 163 a.a., with molecular weight of ~18 kDa.

Human

The MMP-12 protein is potentially involved in tissue injury and remodeling and possesses notable elastolytic activity. It demonstrates the ability to accept both large and small amino acids at the P1' site, although it exhibits a preference for leucine. At the P1 site, it favors aromatic or hydrophobic residues, with a preference for small hydrophobic residues like alanine in the P3 position.

Macrophage metalloelastase; MME; MMP-12; HME

Greater than 90% as determined by reducing SDS-PAGE

1. Lyophilized from a 0.2 μm filtered solution of 10 mM Hepes, 2 mM CaCl 2 , 250 mM NaCl, pH 7.0. Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween 80 are added as protectants before lyophilization. 2. Lyophilized from a 0.2 μm filtered solution of 50 mM Tris, 2 mM CaCl2, 250 mM NaCl, pH 7, 5% Trehalose, 5% Mannitol, 0.01% Tween-80.

Room temperature in continental US; may vary elsewhere.