protein

MST4/STK26 Protein, Human (sf9, GST)

HY-P74741

5 μg;10 μg;50 μg;100 μg

56;90;250;400 USD

MST4/STK26 Protein, Human (sf9, GST)

proteins

Sf9 insect cells

5 μg;10 μg;50 μg;100 μg

56;90;250;400 USD

MST4/STK26 is a kinase that mediates cell growth, regulates apoptosis, and, together with STK24, is involved in negatively affecting Golgi reorientation during RHO-triggered polarized cell migration. MST4/STK26 enhances autophagic flux by phosphorylating ATG4B at 'Ser-383'. MST4/STK26 Protein, Human (sf9, GST) is the recombinant human-derived MST4/STK26 protein, expressed by Sf9 insect cells , with GST labeled tag.

Human

MST4/STK26, a serine/threonine-protein kinase, functions as a mediator of cell growth and plays a modulatory role in apoptosis. Alongside STK24, it participates in the negative regulation of Golgi reorientation during polarized cell migration triggered by RHO activation. Additionally, MST4/STK26 phosphorylates ATG4B at 'Ser-383,' thereby enhancing autophagic flux. These activities highlight its involvement in diverse cellular processes, including growth regulation, apoptotic modulation, and coordination of cellular migration through Golgi reorientation and autophagy modulation.

Serine/threonine-protein kinase 26; MST-4; STK26; MASK

Greater than 95% as determined by reducing SDS-PAGE.

Supplied as a 0.2 μm filtered solution of 20 mM PB, 300 mM NaCl, pH 7.0, 25% glycerol, 0.5 mM TCEP, 0.5 mM EDTA, 0.5 mM GSH.

Shipping with dry ice